The BDI Microfluidics team develops novel micro and nanofluidic technologies leveraging next-generation lab-on-a-chip platforms for life science research and point-of-care diagnostics. The emphasis is on novel multi-force liquid handling schemes, (polymer) micro- and nanofabrication as well as system integration and automation. The main areas of application are biomedical diagnostics and systems biology.
The research in this area is highly interdisciplinary featuring substantial interactions with most other research groups and the industrial partners of the BDI.
More information on the Microfluidics group can be found here.
Charles E. Nwankire, Gerard G. Donohoe, Xin Zhang, Jonathan Siegrist, Martin Somers, Dirk Kurzbuch, Ruairi Monaghan, Maria Kitsara, Robert Burger, Stephen Hearty, Julie Murrell, Christopher Martin, Martha Rook, Louise Barrett, Stephen Daniels, Colette McDonagh, Richard O'Kennedy, and Jens Ducrée. At-line bioprocess monitoring by immunoassay with rotationally controlled serial siphoning and integrated supercritical angle fluorescence optics. Analytica Chimica Acta, 2013. status: in press. [ DOI ]
Macdara Glynn, David Kinahan, and Jens Ducrée. CD4 counting technologies for HIV therapy monitoring in resource-poor settings: State-of-the-art and emerging microtechnologies. Lab on a Chip, 2013. status: in press.
Elizaveta Vereshchagina, Declan McGlade, Macdara Glynn, and Jens Ducrée. A hybrid microfluidic platform for cell-based assays via diffusive and convective trans-membrane perfusion. Biomicrofluidics, 7, 2013. status: in press. [ DOI ]
Robert Burger, Patrick Reith, Gregor Kijanka, Victor Akujobi, Patrick Abgrall, and Jens Ducrée. Array-based capture, distribution, counting and multiplexed assaying of beads on a centrifugal microfluidic platform. Lab on a Chip, 12(7):1289-1295, 2012. [ DOI ]
Daniel Kirby, Jonathan Siegrist, Laëtitia Zavattoni, Robert Burger, and Jens Ducrée. Centrifugo-magnetophoretic particle separation. Microfluidics & Nanofluidics, 13(6):899-908, 2012.
Neus Godino, Robert Gorkin III, Ken Bourke, and Jens Ducrée. Fabricating electrodes for amperometric detection in hybrid paper/polymer lab-on-a-chip devices. Lab on a Chip, 12(18):3281-3284, 2012. [ DOI ]
Llibertat Abad, Francisco Javier del Campo, Francesc Xavier Muñoz, Luis J. Fernández, Daniel Calavia, Gloria Colom, Juan Pablo Salvador, M. Pilar Marco, Vanessa Escamilla-Gómez, Berta Esteban-Fernández de Ávila, Susana Campuzano, María Pedrero, José Manuel Pingarrón, Neus Godino, Robert Gorkin III, and Jens Ducrée. Design and fabrication of a COP-based microfluidic chip: Chronoamperometric detection of Troponin T. Electrophoresis, 33(21):3187-3194, 2012. [ DOI ]
Ivan K. Dimov, Gregor Kijanka, Young Geun Park, Jens Ducrée, Taewook Kang, and Luke P. Lee. Integrated microfluidic array plate (iMAP) for cellular and molecular analysis. Lab on a Chip, 11(16):2701-2710, 2011. selected as hot article. [ DOI ]
Dr. Ducrée holds a Full Professorship of Microsystems in the School of Physical Sciences at DCU, and he has been principal investigator for Microfluidic Platforms at the Biomedical Diagnostics Institute (BDI). Dr Ducrée is also an academic member of the National Centre for Sensor Research (NCSR). His research is mainly directed towards novel microfluidic platforms and associated actuation, detection, fabrication and instrumentation technologies for the integration, automation, miniaturization and parallelization of sample preparation and detection of bioanalytical assays (e.g. immunoassays, nucleic acid testing, general chemistry, cell counting). Typical applications are sample-to-answer systems for biomedical point-of-care and global diagnostics, liquid handling automation for the life sciences (e.g. concentration /purification and amplification of DNA / RNA from a range of biosamples),environmental monitoring and food safety.